CALL FOR PAPERS Cardiovascular and Cerebrovascular Aging – New Mechanisms and Insights Age, aerobic fitness, and cerebral perfusion during exercise: role of carbon dioxide
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چکیده
Daniela Flück, Igor D. Braz, Stefanie Keiser, Fabienne Hüppin, Thomas Haider, Matthias P. Hilty, James P. Fisher, and Carsten Lundby Zürich Center for Integrative Human Physiology (ZIHP), University of Zürich, Zürich, Switzerland; Institute of Physiology, University of Zürich, Zürich, Switzerland; School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom; Exercise Physiology, Institute of Human Movement Sciences, ETH Zürich, Zürich, Switzerland; Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland; Medical Intensive Care Unit, University Hospital of Zürich, Zürich, Switzerland and Food and Nutrition and Sport Science, Gothenburg University, Gothenburg, Sweden
منابع مشابه
Age, aerobic fitness, and cerebral perfusion during exercise: role of carbon dioxide.
Middle cerebral artery mean velocity (MCAvmean) is attenuated with increasing age both at rest and during exercise. The aim of this study was to determine the influence of the age-dependent reduction in arterial Pco2 (PaCO2) and physical fitness herein. We administered supplemental CO2 (CO2 trial) or no additional gas (control trial) to the inspired air in a blinded and randomized manner, and a...
متن کاملElevated aerobic fitness sustained throughout the adult lifespan is associated with improved cerebral hemodynamics.
BACKGROUND AND PURPOSE Age-related impairments in cerebral blood flow and cerebrovascular reactivity to carbon dioxide (CVRCO2) are established risk factors for stroke that respond favorably to aerobic training. The present study examined to what extent cerebral hemodynamics are improved when training is sustained throughout the adult lifespan. METHODS Eighty-one healthy males were prospectiv...
متن کاملCardiorespiratory fitness mediates the effects of aging on cerebral blood flow
The brain's vasculature is likely to be subjected to the same age-related physiological and anatomical changes affecting the rest of the cardiovascular system. Since aerobic fitness is known to alleviate both cognitive and volumetric losses in the brain, it is important to investigate some of the possible mechanisms underlying these beneficial changes. Here we investigated the role that estimat...
متن کاملCardiovascular and cerebral hemodynamics during exercise and recovery in obese individuals as a function of their fitness status
The aim of this study was to compare cardiovascular hemodynamics and cerebral oxygenation/perfusion (COP) during and after maximal incremental exercise in obese individuals according to their aerobic fitness versus age-matched healthy controls (AMHC). Fifty-four middle-aged obese (OB) and 16 AMHC were recruited. Maximal cardiopulmonary function (gas exchange analysis), cardiac hemodynamics (imp...
متن کاملCALL FOR PAPERS Cardiovascular and Cerebrovascular Aging–New Mechanisms and Insights Assessing cerebrovascular autoregulation from critical closing pressure and resistance area product during upright posture in aging and hypertension
Robertson AD, Edgell H, Hughson RL. Assessing cerebrovascular autoregulation from critical closing pressure and resistance area product during upright posture in aging and hypertension. Am J Physiol Heart Circ Physiol 307: H124–H133, 2014. First published May 23, 2014; doi:10.1152/ajpheart.00086.2014.—Static cerebral autoregulation (sCA) is believed to be resistant to aging and hypertensive pat...
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تاریخ انتشار 2014